Search results for "EFO_0001645"

All results
24
Traits
4
Publications
20

coronary artery disease

EFO_0001645
Cardiovascular disease
Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction. (ACC) [NCIT: C26732]
Associated PGS 77 Show Reported Traits

spontaneous coronary artery dissection

EFO_0010820
Cardiovascular disease
The spontaneous occurrence of a dissection of the coronary artery. The clinical recognition of this phenomenon has increased as coronary angiography is becoming more commonly used in the treatment of acute coronary syndrome. The etiology of the condition has not been fully elucidated, but the mean age of presentation is 30-45 years, more than 70% are women, and 30% of cases occur in the peripartum period.
Associated PGS 1 Show Reported Traits

Myocardial Ischemia

EFO_1001375
Cardiovascular disease
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (coronary artery disease), to obstruction by a thrombus (coronary thrombosis), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (myocardial infarction). [MESH: D017202]
Associated PGS 1 Show Reported Traits
Gola D et al. (2020) - Circ Genom Precis MedPMID:33170024doi:10.1161/circgen.120.002932PGP000152
PGS developed 4 - PGS evaluated 6
Patel AP et al. (2023) - Nat MedPMID:37414900doi:10.1038/s41591-023-02429-xPGP000466
PGS developed 3 - PGS evaluated 3
Smith JL et al. (2024) - Circ Genom Precis MedPMID:38380516doi:10.1161/circgen.123.004272PGP000602
PGS developed 3 - PGS evaluated 3
Aragam KG et al. (2022) - Nat GenetPMID:36474045doi:10.1038/s41588-022-01233-6PGP000409
PGS developed 2 - PGS evaluated 2
Abramowitz SA et al. (2024) - JAMAPMID:39549270doi:10.1001/jama.2024.23784PGP000684
PGS developed 2 - PGS evaluated 2

coronary atherosclerosis

MONDO_0021661
Cardiovascular disease
Atherosclerosis of the coronary vasculature. [NCIT: C35505]
Associated PGS 2 Show Reported Traits
Tada H et al. (2015) - Eur Heart JPMID:26392438doi:10.1093/eurheartj/ehv462PGP000004
PGS developed 1 - PGS evaluated 2
Abraham G et al. (2016) - Eur Heart JPMID:27655226doi:10.1093/eurheartj/ehw450PGP000005
PGS developed 1 - PGS evaluated 2
Koyama S et al. (2020) - Nat GenetPMID:33020668doi:10.1038/s41588-020-0705-3PGP000104
PGS developed 1 - PGS evaluated 1
Paquette M et al. (2017) - J Clin LipidolPMID:28456682doi:10.1016/j.jacl.2017.03.019PGP000009
PGS developed 1 - PGS evaluated 1
Wang M et al. (2020) - J Am Coll CardiolPMID:32762905doi:10.1016/j.jacc.2020.06.024PGP000090
PGS developed 1 - PGS evaluated 2
Tikkanen E et al. (2013) - Arterioscler Thromb Vasc BiolPMID:23599444doi:10.1161/atvbaha.112.301120PGP000082
PGS developed 1 - PGS evaluated 1
Mega JL et al. (2015) - LancetPMID:25748612doi:10.1016/S0140-6736(14)61730-XPGP000003
PGS developed 1 - PGS evaluated 1
Natarajan P et al. (2017) - CirculationPMID:28223407doi:10.1161/CIRCULATIONAHA.116.024436PGP000042
PGS developed 1 - PGS evaluated 1
Morieri ML et al. (2018) - Diabetes CarePMID:30262460doi:10.2337/dc18-0709PGP000043
PGS developed 1 - PGS evaluated 1
Inouye M et al. (2018) - J Am Coll CardiolPMID:30309464doi:10.1016/j.jacc.2018.07.079PGP000007
PGS developed 1 - PGS evaluated 3
Hajek C et al. (2018) - Circ Genom Precis MedPMID:30354305doi:10.1161/CIRCGEN.118.002324PGP000044
PGS developed 1 - PGS evaluated 1
Pechlivanis S et al. (2020) - BMC Med GenetPMID:32912153doi:10.1186/s12881-020-01113-yPGP000114
PGS developed 1 - PGS evaluated 1
Severance LM et al. (2019) - J Cardiovasc Comput TomogrPMID:31104941doi:10.1016/j.jcct.2019.05.005PGP000187
PGS developed 1 - PGS evaluated 1
Bauer A et al. (2021) - Genet EpidemiolPMID:34082474doi:10.1002/gepi.22389PGP000202
PGS developed 1 - PGS evaluated 2
Feitosa MF et al. (2021) - Circ Genom Precis MedPMID:33844929doi:10.1161/circgen.120.003201PGP000232
PGS developed 1 - PGS evaluated 1