Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000853
(T2D_Insulin_Secretion_2)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000853/ScoringFiles/PGS000853.txt.gz
PGS000854
(T2D_BetaCell)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with beta cell function) type 2 diabetes mellitus 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz
PGS000855
(T2D_Lipodystrophy)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with lipodystrophy) type 2 diabetes mellitus 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000855/ScoringFiles/PGS000855.txt.gz
PGS000856
(T2D_LiverLipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with liver lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000856/ScoringFiles/PGS000856.txt.gz
PGS000857
(T2D_Obesity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with obesity) type 2 diabetes mellitus 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000857/ScoringFiles/PGS000857.txt.gz
PGS000858
(T2D_Proinsulin)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with proinsulin levels) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000858/ScoringFiles/PGS000858.txt.gz
PGS000859
(CKD)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Chronic kidney disease chronic kidney disease 34
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000859/ScoringFiles/PGS000859.txt.gz
PGS000860
(eGFR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Estimated glomerular filtration rate glomerular filtration rate 625
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000860/ScoringFiles/PGS000860.txt.gz
PGS000861
(UACR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Urine Albumin-to-Creatinine ratio urinary albumin to creatinine ratio 93
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000861/ScoringFiles/PGS000861.txt.gz
PGS000862
(DR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Diabetic Retinopathy diabetic retinopathy 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000862/ScoringFiles/PGS000862.txt.gz
PGS000863
(Cardiovascular)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Cardiovascular disease cardiovascular disease 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000863/ScoringFiles/PGS000863.txt.gz
PGS000864
(T2D-gPRS)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 389,243
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000864/ScoringFiles/PGS000864.txt.gz
PGS000865
(PRS-HFC)
 PGP000212 |
Dongiovanni P et al. J Intern Med (2017)
 Hepatic fat content liver fat measurement 4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000865/ScoringFiles/PGS000865.txt.gz
PGS000866
(PRS-HFC_SOS)
 PGP000212 |
Dongiovanni P et al. J Intern Med (2017)
 Hepatic fat content liver fat measurement 4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000866/ScoringFiles/PGS000866.txt.gz
PGS000867
(GRS10_Allergy)
 PGP000213 |
Arabkhazaeli A et al. Pediatr Allergy Immunol (2017)
 Allergy allergic disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000867/ScoringFiles/PGS000867.txt.gz
PGS000868
(T2D_221)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 221
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000868/ScoringFiles/PGS000868.txt.gz
PGS000869
(T1D_48)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000869/ScoringFiles/PGS000869.txt.gz
PGS000870
(CFRD_18)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Cystic fibrosis related diabetes complication 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000870/ScoringFiles/PGS000870.txt.gz
PGS000871
(IS_14)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Insulin secretion insulin secretion trait 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000871/ScoringFiles/PGS000871.txt.gz
PGS000872
(PRS-5)
 PGP000215 |
Bianco C et al. J Hepatol (2020)
 Non-alcoholic fatty liver disease non-alcoholic fatty liver disease 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000872/ScoringFiles/PGS000872.txt.gz
PGS000873
(SNP143)
 PGP000216 |
Brentnall AR et al. Int J Cancer (2019)
 Breast cancer breast carcinoma 143
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000873/ScoringFiles/PGS000873.txt.gz
PGS000874
(PRS41_CLL)
 PGP000220 |
Kleinstern G et al. Blood (2018)
 Chronic lymphocytic leukemia chronic lymphocytic leukemia 41
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000874/ScoringFiles/PGS000874.txt.gz
PGS000875
(PGS36_LDLc)
 PGP000221 |
Leal LG et al. Mol Genet Genomic Med (2020)
 LDL cholesterol low density lipoprotein cholesterol measurement 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000875/ScoringFiles/PGS000875.txt.gz
PGS000876
(PRS31_AD)
 PGP000222 |
Leonenko G et al. Ann Clin Transl Neurol (2019)
 Alzheimer's disease Alzheimer disease 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000876/ScoringFiles/PGS000876.txt.gz
PGS000877
(uwGRS53_IR)
 PGP000223 |
Lotta LA et al. Nat Genet (2016)
 Insulin resistance insulin resistance 53
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000877/ScoringFiles/PGS000877.txt.gz
PGS000878
(PRS4_PC)
 PGP000224 |
Oh JJ et al. Front Oncol (2020)
 Prostate cancer prostate carcinoma 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000878/ScoringFiles/PGS000878.txt.gz
PGS000879
(PRS146_IOP)
 PGP000225 |
Qassim A et al. Ophthalmology (2020)
 Intraocular pressure intraocular pressure measurement 146
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000879/ScoringFiles/PGS000879.txt.gz
PGS000880
(PRS18_LC)
 PGP000226 |
Xie J et al. Sleep (2021)
 Lung cancer lung carcinoma 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000880/ScoringFiles/PGS000880.txt.gz
PGS000881
(GRS72_PCa)
 PGP000227 |
Xu J et al. Prostate (2021)
 Prostate cancer prostate carcinoma 72
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000881/ScoringFiles/PGS000881.txt.gz
PGS000882
(25OHD_SBayesR_PGS)
 PGP000228 |
Revez JA et al. Nat Commun (2020)
 25-hydroxyvitamin D vitamin D measurement 1,094,650
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000882/ScoringFiles/PGS000882.txt.gz
PGS000883
(eGFR_LDpredPRS)
 PGP000229 |
Yu Z et al. J Am Soc Nephrol (2021)
 Estimated glomerular filtration rate glomerular filtration rate 1,477,661
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000883/ScoringFiles/PGS000883.txt.gz
PGS000884
(eGFR_PTPRS)
 PGP000229 |
Yu Z et al. J Am Soc Nephrol (2021)
 Estimated glomerular filtration rate glomerular filtration rate 40,042
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000884/ScoringFiles/PGS000884.txt.gz
PGS000885
(eGFR_TOPSNPPRS)
 PGP000229 |
Yu Z et al. J Am Soc Nephrol (2021)
 Estimated glomerular filtration rate glomerular filtration rate 1,460
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000885/ScoringFiles/PGS000885.txt.gz
PGS000886
(GLGC_2021_AFR_LDL_PRS_weights_PRS-CS)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,222,318
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000886/ScoringFiles/PGS000886.txt.gz
PGS000887
(GLGC_2021_AFR_LDL_PRS_weights_PT)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 295
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000887/ScoringFiles/PGS000887.txt.gz
PGS000888
(GLGC_2021_ALL_LDL_PRS_weights_PRS-CS)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,239,184
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000888/ScoringFiles/PGS000888.txt.gz
PGS000889
(GLGC_2021_ALL_LDL_PRS_weights_PT)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 9,009
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000889/ScoringFiles/PGS000889.txt.gz
PGS000890
(GLGC_2021_EAS_LDL_PRS_weights_PRS-CS)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,029,158
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000890/ScoringFiles/PGS000890.txt.gz
PGS000891
(GLGC_2021_EAS_LDL_PRS_weights_PT)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 66
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000891/ScoringFiles/PGS000891.txt.gz
PGS000892
(GLGC_2021_EUR_LDL_PRS_weights_PRS-CS)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,119,211
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000892/ScoringFiles/PGS000892.txt.gz
PGS000893
(GLGC_2021_EUR_LDL_PRS_weights_PT)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 5,427
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000893/ScoringFiles/PGS000893.txt.gz
PGS000894
(GLGC_2021_HIS_LDL_PRS_weights_PRS-CS)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,175,595
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000894/ScoringFiles/PGS000894.txt.gz
PGS000895
(GLGC_2021_HIS_LDL_PRS_weights_PT)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 76
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000895/ScoringFiles/PGS000895.txt.gz
PGS000896
(GLGC_2021_SAS_LDL_PRS_weights_PRS-CS)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,100,062
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000896/ScoringFiles/PGS000896.txt.gz
PGS000897
(GLGC_2021_SAS_LDL_PRS_weights_PT)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 13
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000897/ScoringFiles/PGS000897.txt.gz
PGS000898
(PRS39_AD)
 PGP000231 |
de Rojas I et al. Nat Commun (2021)
 Alzheimer's disease Alzheimer disease 40
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000898/ScoringFiles/PGS000898.txt.gz
PGS000899
(PRS176_CHD)
 PGP000232 |
Feitosa MF et al. Circ Genom Precis Med (2021)
 Coronary heart disease coronary artery disease 176
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000899/ScoringFiles/PGS000899.txt.gz
PGS000900
(PRS_SBP_f)
 PGP000233 |
Kauko A et al. Hypertension (2021)
 Systolic blood pressure (female) systolic blood pressure,
female		 1,098,015
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000900/ScoringFiles/PGS000900.txt.gz
PGS000901
(PRS_SBP_m)
 PGP000233 |
Kauko A et al. Hypertension (2021)
 Systolic blood pressure (male) systolic blood pressure,
male		 1,098,015
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000901/ScoringFiles/PGS000901.txt.gz
PGS000902
(PRS90_PD)
 PGP000235 |
Nalls MA et al. Lancet Neurol (2019)
 Parkinson's disease Parkinson disease 90
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000902/ScoringFiles/PGS000902.txt.gz
Showing 851 to 900 of 5091 rows