Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003373
(GSCAN_DrnkWk_2022_PRS_WEIGHTS_AFR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Drinks per week alcohol consumption quality 1,177,071
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003373/ScoringFiles/PGS003373.txt.gz
PGS003374
(GSCAN_DrnkWk_2022_PRS_WEIGHTS_AMR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Drinks per week alcohol consumption quality 1,109,568
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003374/ScoringFiles/PGS003374.txt.gz
PGS003375
(GSCAN_DrnkWk_2022_PRS_WEIGHTS_EAS)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Drinks per week alcohol consumption quality 856,333
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003375/ScoringFiles/PGS003375.txt.gz
PGS003376
(GSCAN_DrnkWk_2022_PRS_WEIGHTS_EUR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Drinks per week alcohol consumption quality 1,055,988
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003376/ScoringFiles/PGS003376.txt.gz
PGS003377
(eGFRldpred_PGS)
 PGP000411 |
Steinbrenner I et al. Kidney Int (2022)
 Estimated glomerular filtration rate glomerular filtration rate 1,496,254
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003377/ScoringFiles/PGS003377.txt.gz
PGS003378
(PSA_PGS_128)
 PGP000412 |
Kachuri L et al. Nat Med (2023)
 Prostate-specific antigen (PSA) levels prostate specific antigen amount 128
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003378/ScoringFiles/PGS003378.txt.gz
PGS003379
(PSA_PGS_CSx)
 PGP000412 |
Kachuri L et al. Nat Med (2023)
 Prostate-specific antigen (PSA) levels prostate specific antigen amount 1,071,278
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003379/ScoringFiles/PGS003379.txt.gz
PGS003380
(best_BRCA)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Breast cancer breast carcinoma 1,142,637
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003380/ScoringFiles/PGS003380.txt.gz
PGS003381
(best_UCEC)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Uterine endometrial carcinoma endometrial carcinoma 529,365
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003381/ScoringFiles/PGS003381.txt.gz
PGS003382
(best_SKCM)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Skin cutaneous melanoma cutaneous melanoma 672
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003382/ScoringFiles/PGS003382.txt.gz
PGS003383
(best_PRAD)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Prostate adenocarcinoma prostate adenocarcinoma 168,700
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003383/ScoringFiles/PGS003383.txt.gz
PGS003384
(best_GBM)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Glioblastoma glioblastoma 910
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003384/ScoringFiles/PGS003384.txt.gz
PGS003385
(best_OV)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Ovarian serous carcinoma ovarian serous carcinoma 144,810
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003385/ScoringFiles/PGS003385.txt.gz
PGS003386
(best_COADREAD)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Colorectal cancer colorectal carcinoma 61
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003386/ScoringFiles/PGS003386.txt.gz
PGS003387
(best_ESCA_BEEA)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Esophageal adenocarcinoma or Barrett’s esophagus Barrett's esophagus,
esophageal adenocarcinoma		 601,980
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003387/ScoringFiles/PGS003387.txt.gz
PGS003388
(best_ESCA_EA)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Esophageal adenocarcinoma esophageal adenocarcinoma 356,743
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003388/ScoringFiles/PGS003388.txt.gz
PGS003389
(best_CESC)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Cervical cancer cervical carcinoma 2,814
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003389/ScoringFiles/PGS003389.txt.gz
PGS003390
(best_HNSC)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Head and neck squamous cell carcinoma head and neck squamous cell carcinoma 931,477
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003390/ScoringFiles/PGS003390.txt.gz
PGS003391
(best_LUCA)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Lung cancer lung carcinoma 133
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003391/ScoringFiles/PGS003391.txt.gz
PGS003392
(best_LUSC)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Lung squamous cell carcinoma squamous cell lung carcinoma 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003392/ScoringFiles/PGS003392.txt.gz
PGS003393
(best_LUAD)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Lung adenocarcinoma lung adenocarcinoma 74
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003393/ScoringFiles/PGS003393.txt.gz
PGS003394
(PRS_Stepwise)
 PGP000277 |
Dareng EO et al. Eur J Hum Genet (2022)
 Epithelial ovarian cancer ovarian carcinoma 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003394/ScoringFiles/PGS003394.txt.gz
PGS003395
(PRScsx_CRC)
 PGP000414 |
Xin J et al. Genome Med (2023)
 Colorectal cancer colorectal cancer 1,145,689
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003395/ScoringFiles/PGS003395.txt.gz
PGS003396
(PRS-11ASN)
 PGP000415 |
Jee YH et al. Int J Epidemiol (2022)
 Breast cancer breast carcinoma 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003396/ScoringFiles/PGS003396.txt.gz
PGS003397
(PRS-42ASN)
 PGP000415 |
Jee YH et al. Int J Epidemiol (2022)
 Breast cancer breast carcinoma 42
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003397/ScoringFiles/PGS003397.txt.gz
PGS003398
(PRS-136EUR)
 PGP000415 |
Jee YH et al. Int J Epidemiol (2022)
 Breast cancer breast carcinoma 136
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003398/ScoringFiles/PGS003398.txt.gz
PGS003399
(PRS-209EUR)
 PGP000415 |
Jee YH et al. Int J Epidemiol (2022)
 Breast cancer breast carcinoma 209
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003399/ScoringFiles/PGS003399.txt.gz
PGS003400
(PRS97_obesity)
 PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
 Obesity obesity 97
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003400/ScoringFiles/PGS003400.txt.gz
PGS003401
(TG.PS)
 PGP000418 |
Pieri K et al. Int J Cardiol (2022)
 Triglyceride levels triglyceride measurement 108
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003401/ScoringFiles/PGS003401.txt.gz
PGS003402
(PRS_T2D)
 PGP000419 |
Lamri A et al. Elife (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,838
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003402/ScoringFiles/PGS003402.txt.gz
PGS003403
(PRS28_LDL)
 PGP000420 |
Trinder M et al. J Am Coll Cardiol (2019)
 LDL cholesterol low density lipoprotein cholesterol measurement 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003403/ScoringFiles/PGS003403.txt.gz
PGS003404
(wGRS)
 PGP000421 |
Wang J et al. Arterioscler Thromb Vasc Biol (2016)
 LDL cholesterol low density lipoprotein cholesterol measurement 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003404/ScoringFiles/PGS003404.txt.gz
PGS003405
(165SNP_PRS)
 PGP000422 |
Vanhoye X et al. Transl Res (2022)
 LDL cholesterol low density lipoprotein cholesterol measurement 169
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003405/ScoringFiles/PGS003405.txt.gz
PGS003406
(1_withUKB_sexAll_metaGRS.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm 6,852,195
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003406/ScoringFiles/PGS003406.txt.gz
PGS003407
(2_withUKB_sexMale_metaGRS.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm,
male		 6,618,190
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003407/ScoringFiles/PGS003407.txt.gz
PGS003408
(3_withUKB_sexFemale_metaGRS.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm,
female		 6,671,269
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003408/ScoringFiles/PGS003408.txt.gz
PGS003409
(4_withUKB_sexAll_IAonly.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm 6,852,195
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003409/ScoringFiles/PGS003409.txt.gz
PGS003410
(5_withUKB_sexMale_IAonly.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm,
male		 6,618,190
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003410/ScoringFiles/PGS003410.txt.gz
PGS003411
(6_withUKB_sexFemale_IAonly.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm,
female		 6,671,269
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003411/ScoringFiles/PGS003411.txt.gz
PGS003412
(PRS28_melanoma)
 PGP000424 |
Olsen CM et al. Br J Dermatol (2019)
 Melanoma melanoma 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003412/ScoringFiles/PGS003412.txt.gz
PGS003413
(rvPRS_IOP)
 PGP000426 |
Gao XR et al. Nat Commun (2022)
 Intraocular pressure intraocular pressure measurement 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003413/ScoringFiles/PGS003413.txt.gz
PGS003414
(PRS47_RBD)
 PGP000427 |
Krohn L et al. Nat Commun (2022)
 REM sleep behavior disorder REM sleep behavior disorder 47
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003414/ScoringFiles/PGS003414.txt.gz
PGS003415
(PGS268_PCa)
 PGP000428 |
Nyberg T et al. J Clin Oncol (2022)
 Prostate cancer prostate carcinoma 268
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003415/ScoringFiles/PGS003415.txt.gz
PGS003416
(MTAGPRS)
 PGP000429 |
Seviiri M et al. Nat Commun (2022)
 Basal cell carcinoma (MTAG) basal cell carcinoma 462
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003416/ScoringFiles/PGS003416.txt.gz
PGS003417
(UKBPRS)
 PGP000429 |
Seviiri M et al. Nat Commun (2022)
 Basal cell carcinoma basal cell carcinoma 273
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003417/ScoringFiles/PGS003417.txt.gz
PGS003418
(PRState_Eur)
 PGP000430 |
Pagadala MS et al. BMC Cancer (2022)
 Prostate cancer prostate cancer 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003418/ScoringFiles/PGS003418.txt.gz
PGS003419
(PRState_Trans)
 PGP000430 |
Pagadala MS et al. BMC Cancer (2022)
 Prostate cancer prostate cancer 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003419/ScoringFiles/PGS003419.txt.gz
PGS003420
(PRS100_PRScs)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 100
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003420/ScoringFiles/PGS003420.txt.gz
PGS003421
(PRS16_C+T)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003421/ScoringFiles/PGS003421.txt.gz
PGS003422
(PRS16_PRSice2)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003422/ScoringFiles/PGS003422.txt.gz
Showing 3301 to 3350 of 5091 rows